Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption.

Guan Y, Hao C, Cha DR, Rao R, Lu W, Kohan DE, Magnuson MA, Redha R, Zhang Y, Breyer MD
Nat Med. 2005 11 (8): 861-6

PMID: 16007095 · DOI:10.1038/nm1278

MeSH Terms (19)

Amiloride Analysis of Variance Animals Blood Chemical Analysis Body Fluids Body Weight Chromatin Immunoprecipitation Diabetes Mellitus, Type 2 Epithelial Sodium Channels Gene Targeting Mice Mice, Transgenic Nephrons PPAR gamma Reverse Transcriptase Polymerase Chain Reaction Sodium Sodium Channels Thiazolidinediones Water-Electrolyte Balance

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