Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.

Egli M, Minasov G, Tereshko V, Pallan PS, Teplova M, Inamati GB, Lesnik EA, Owens SR, Ross BS, Prakash TP, Manoharan M
Biochemistry. 2005 44 (25): 9045-57

PMID: 15966728 · DOI:10.1021/bi050574m

MeSH Terms (16)

Base Sequence Biophysical Phenomena Biophysics Crystallization Crystallography, X-Ray DNA Enzyme Stability Exonucleases Models, Molecular Nucleic Acid Conformation Nucleic Acid Denaturation Oligonucleotides Ribonucleases RNA Static Electricity Temperature

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