The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.

Meredith EJ, Holder MJ, Chamba A, Challa A, Drake-Lee A, Bunce CM, Drayson MT, Pilkington G, Blakely RD, Dyer MJ, Barnes NM, Gordon J
FASEB J. 2005 19 (9): 1187-9

PMID: 15870169 · DOI:10.1096/fj.04-3477fje

MeSH Terms (14)

Antineoplastic Agents Apoptosis ATP Binding Cassette Transporter, Subfamily B, Member 1 Burkitt Lymphoma Cell Line, Tumor Clomipramine Fenfluramine Fluoxetine Humans Lymphoma, B-Cell N-Methyl-3,4-methylenedioxyamphetamine Proto-Oncogene Proteins c-bcl-2 Psychotropic Drugs Serotonin Plasma Membrane Transport Proteins

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