Cytochrome P450 3A4-catalyzed testosterone 6beta-hydroxylation stereochemistry, kinetic deuterium isotope effects, and rate-limiting steps.

Krauser JA, Guengerich FP
J Biol Chem. 2005 280 (20): 19496-506

PMID: 15772082 · DOI:10.1074/jbc.M501854200

MeSH Terms (14)

Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System Deuterium Humans Hydroxylation In Vitro Techniques Kinetics Molecular Structure Oxidation-Reduction Recombinant Proteins Stereoisomerism Substrate Specificity Testosterone Thermodynamics

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