Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.

Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, Lee VM, Hersh LB, Sapolsky RM, Mirnics K, Sisodia SS
Cell. 2005 120 (5): 701-13

PMID: 15766532 · DOI:10.1016/j.cell.2005.01.015

MeSH Terms (20)

Alzheimer Disease Amyloid beta-Peptides Amyloid beta-Protein Precursor Animals Cerebral Cortex Disease Models, Animal Down-Regulation Environment Exploratory Behavior Gene Expression Regulation Male Membrane Proteins Mice Mice, Transgenic Neprilysin Nerve Tissue Proteins Oligonucleotide Array Sequence Analysis Plaque, Amyloid Presenilin-1 Up-Regulation

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