Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins.

Bakin AV, Stourman NV, Sekhar KR, Rinehart C, Yan X, Meredith MJ, Arteaga CL, Freeman ML
Free Radic Biol Med. 2005 38 (3): 375-87

PMID: 15629866 · DOI:10.1016/j.freeradbiomed.2004.10.033

MeSH Terms (19)

Activating Transcription Factor 3 Animals Catalase Cell Line DNA-Binding Proteins Gene Expression Regulation Glutamate-Cysteine Ligase Glutathione Glutathione Transferase Humans Inactivation, Metabolic Mice Reactive Oxygen Species RNA, Messenger Signal Transduction Smad3 Protein Trans-Activators Transcription Factors Transforming Growth Factor beta

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