Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.

Gainer JV, Bellamine A, Dawson EP, Womble KE, Grant SW, Wang Y, Cupples LA, Guo CY, Demissie S, O'Donnell CJ, Brown NJ, Waterman MR, Capdevila JH
Circulation. 2005 111 (1): 63-9

PMID: 15611369 · DOI:10.1161/01.CIR.0000151309.82473.59

MeSH Terms (34)

Adult Aged Alleles Amino Acid Substitution Arachidonic Acid Blacks Blood Pressure Codon Cohort Studies Comorbidity Cytochrome P-450 CYP4A Cytochrome P-450 Enzyme System DNA Mutational Analysis Female Gene Frequency Genetic Predisposition to Disease Genetic Variation Genotype Humans Hydroxyeicosatetraenoic Acids Hypertension Introns Kidney Lauric Acids Male Middle Aged Multifactorial Inheritance Mutagenesis, Insertional Mutation, Missense Point Mutation Sequence Deletion Tennessee United States Whites

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