Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation.

Bussière FI, Chaturvedi R, Cheng Y, Gobert AP, Asim M, Blumberg DR, Xu H, Kim PY, Hacker A, Casero RA, Wilson KT
J Biol Chem. 2005 280 (4): 2409-12

PMID: 15548540 · DOI:10.1074/jbc.C400498200

MeSH Terms (25)

Animals Apoptosis Cell Line Coculture Techniques Dose-Response Relationship, Drug Helicobacter pylori Immune System Immunoblotting Immunoprecipitation Macrophages Male Mice Mice, Inbred C57BL Monocytes Nitric Oxide Nitric Oxide Synthase Nitric Oxide Synthase Type II Protein Biosynthesis Reverse Transcriptase Polymerase Chain Reaction Risk RNA, Small Interfering Spermine Stomach Neoplasms Transfection Up-Regulation

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