The membrane-anchored serine protease, TMPRSS2, activates PAR-2 in prostate cancer cells.

Wilson S, Greer B, Hooper J, Zijlstra A, Walker B, Quigley J, Hawthorne S
Biochem J. 2005 388 (Pt 3): 967-72

PMID: 15537383 · PMCID: PMC1183478 · DOI:10.1042/BJ20041066

MeSH Terms (15)

Boron Compounds Calcium Catalysis Cell Line, Tumor Humans Male Prostatic Neoplasms Receptor, PAR-2 Recombinant Proteins RNA, Messenger Serine Endopeptidases Serine Proteinase Inhibitors Signal Transduction Substrate Specificity Suramin

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