Mutation spectrum and sequence alkylation selectivity resulting from modification of bacteriophage M13mp18 DNA with S-(2-chloroethyl)glutathione. Evidence for a role of S-(2-N7-guanyl)ethyl)glutathione as a mutagenic lesion formed from ethylene dibromide.

Cmarik JL, Humphreys WG, Bruner KL, Lloyd RS, Tibbetts C, Guengerich FP
J Biol Chem. 1992 267 (10): 6672-9

PMID: 1551876

MeSH Terms (10)

Alkylation Bacteriophages Base Sequence DNA, Viral DNA Adducts Ethylene Dibromide Genes, Viral Glutathione Molecular Sequence Data Mutation

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