Association of mycoplasma and human immunodeficiency virus infection: detection of amplified Mycoplasma fermentans DNA in blood.

Hawkins RE, Rickman LS, Vermund SH, Carl M
J Infect Dis. 1992 165 (3): 581-5

PMID: 1538164 · DOI:10.1093/infdis/165.3.581

A cross-sectional study was undertaken to determine the prevalence of Mycoplasma fermentans infection in patients with human immunodeficiency virus (HIV) infection using polymerase chain reaction methodology. Targeted M. fermentans DNA sequences could be amplified from the DNA extracted from the blood of 6 (11%) of 55 HIV-seropositive patients but from none of 26 HIV-seronegative subjects at low risk for HIV infection (P = .17). There was no correlation between M. fermentans infection and HIV clinical stage. There was a nonsignificant trend toward an association between M. fermentans infection and a history of syphilis. Infection with M. fermentans may occur more commonly in HIV-infected patients; however, a role as a copathogen or opportunistic infection was not established in this study.

MeSH Terms (18)

Adult Base Sequence Blotting, Southern Cross-Sectional Studies DNA, Bacterial DNA Probes Electrophoresis, Agar Gel Female Gene Amplification HIV Infections Humans Male Molecular Sequence Data Mycoplasma fermentans Mycoplasma Infections Polymerase Chain Reaction Prevalence Syphilis

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