NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.

Huth JR, Yu L, Collins I, Mack J, Mendoza R, Isaac B, Braddock DT, Muchmore SW, Comess KM, Fesik SW, Clore GM, Levens D, Hajduk PJ
J Med Chem. 2004 47 (20): 4851-7

PMID: 15369388 · DOI:10.1021/jm0497803

MeSH Terms (18)

Binding Sites Combinatorial Chemistry Techniques DNA, Single-Stranded DNA-Binding Proteins DNA Helicases Drug Design Genes, myc Humans Inhibitory Concentration 50 Ligands Magnetic Resonance Spectroscopy Models, Molecular Promoter Regions, Genetic Protein Conformation Protein Structure, Tertiary Repetitive Sequences, Amino Acid RNA-Binding Proteins Structure-Activity Relationship

Connections (1)

This publication is referenced by other Labnodes entities:

Links