Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.

Ahn D, Ge Y, Stricklett PK, Gill P, Taylor D, Hughes AK, Yanagisawa M, Miller L, Nelson RD, Kohan DE
J Clin Invest. 2004 114 (4): 504-11

PMID: 15314687 · PMCID: PMC503768 · DOI:10.1172/JCI21064

MeSH Terms (20)

Aldosterone Amiloride Animals Blood Pressure Diuretics Endothelin-1 Furosemide Heterozygote Homozygote Hypernatremia Hypertension In Situ Hybridization Kidney Tubules, Collecting Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic RNA, Messenger Sodium Chloride, Dietary Weight Gain

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