Activation of bis-electrophiles to mutagenic conjugates by human O6-alkylguanine-DNA alkyltransferase.

Valadez JG, Liu L, Loktionova NA, Pegg AE, Guengerich FP
Chem Res Toxicol. 2004 17 (7): 972-82

PMID: 15257623 · DOI:10.1021/tx049897u

MeSH Terms (11)

Biotransformation Dose-Response Relationship, Drug Escherichia coli Humans Hydrocarbons, Halogenated Mutagenicity Tests Mutagens Mutation O(6)-Methylguanine-DNA Methyltransferase Salmonella typhimurium Structure-Activity Relationship

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