Induction of polyamine oxidase 1 by Helicobacter pylori causes macrophage apoptosis by hydrogen peroxide release and mitochondrial membrane depolarization.

Chaturvedi R, Cheng Y, Asim M, Bussière FI, Xu H, Gobert AP, Hacker A, Casero RA, Wilson KT
J Biol Chem. 2004 279 (38): 40161-73

PMID: 15247269 · DOI:10.1074/jbc.M401370200

MeSH Terms (19)

Acetyltransferases Animals Apoptosis Caspase 3 Caspases Cell Line Cytochromes c Enzyme Induction Gene Expression Regulation, Enzymologic Helicobacter Infections Helicobacter pylori Hydrogen Peroxide In Situ Nick-End Labeling Macrophages Membrane Potentials Mice Mitochondria Ornithine Decarboxylase Oxidoreductases Acting on CH-NH Group Donors

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