Generation of new protein kinase inhibitors utilizing cytochrome p450 mutant enzymes for indigoid synthesis.

Guengerich FP, Sorrells JL, Schmitt S, Krauser JA, Aryal P, Meijer L
J Med Chem. 2004 47 (12): 3236-41

PMID: 15163202 · DOI:10.1021/jm030561b

MeSH Terms (13)

Aryl Hydrocarbon Hydroxylases CDC2 Protein Kinase Chromatography, High Pressure Liquid Cyclin-Dependent Kinase 5 Cyclin-Dependent Kinases Cytochrome P-450 CYP2A6 Escherichia coli Glycogen Synthase Kinase 3 Humans Indoles Mixed Function Oxygenases Mutation Protein Kinase Inhibitors

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