Smad3 has a critical role in TGF-beta-mediated growth inhibition and apoptosis in colonic epithelial cells.

Mithani SK, Balch GC, Shiou SR, Whitehead RH, Datta PK, Beauchamp RD
J Surg Res. 2004 117 (2): 296-305

PMID: 15047135 · DOI:10.1016/S0022-4804(03)00335-4

MeSH Terms (15)

Animals Apoptosis Cell Division Cell Line Colon DNA-Binding Proteins Growth Inhibitors Intestinal Mucosa Mice Mice, Transgenic Mutation Promoter Regions, Genetic Smad3 Protein Trans-Activators Transforming Growth Factor beta

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