Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism.

Carrier EJ, Kearn CS, Barkmeier AJ, Breese NM, Yang W, Nithipatikom K, Pfister SL, Campbell WB, Hillard CJ
Mol Pharmacol. 2004 65 (4): 999-1007

PMID: 15044630 · DOI:10.1124/mol.65.4.999

MeSH Terms (15)

Analysis of Variance Animals Arachidonic Acids Cannabinoid Receptor Modulators Cell Division Cells, Cultured Endocannabinoids Enzyme Activation Flow Cytometry Glycerides Macrophage Colony-Stimulating Factor Microglia Mitogen-Activated Protein Kinases Rats Receptor, Cannabinoid, CB2

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