Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.

Andrieux L, Langou√ęt S, Fautrel A, Ezan F, Krauser JA, Savouret JF, Guengerich FP, Baffet G, Guillouzo A
Mol Pharmacol. 2004 65 (4): 934-43

PMID: 15044623 · DOI:10.1124/mol.65.4.934

MeSH Terms (19)

Animals Butadienes Cells, Cultured Cytochrome P-450 CYP1A1 Dose-Response Relationship, Drug Enzyme Induction Enzyme Inhibitors Hepatocytes Humans Male MAP Kinase Signaling System Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinases Nitriles Rats Rats, Sprague-Dawley Receptors, Aryl Hydrocarbon Signal Transduction Time Factors

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