Bves expression during avian embryogenesis.

Osler ME, Bader DM
Dev Dyn. 2004 229 (3): 658-67

PMID: 14991721 · DOI:10.1002/dvdy.10490

Bves (blood vessel/epicardial substance) is a transmembrane protein postulated to play a role in cell adhesion. While it is clear that Bves and gene products of the same family are expressed in adult striated muscle cells, the distribution of these proteins during development has not been critically examined. An understanding of the expression pattern of Bves is essential for a determination of protein function and its role in embryogenesis. In this study, we present an expression analysis of Bves during chick gastrulation and germ layer formation. Our data show that Bves is expressed in epithelia of all three germ layers early in development. Furthermore, Bves protein is observed in epithelial tissues during organogenesis, specifically the developing epidermis, the gut endoderm, and the epicardium of the heart. These data support the hypothesis that Bves may play a role in cell adhesion and movement of epithelia during early embryogenesis.

Copyright 2004 Wiley-Liss, Inc.

MeSH Terms (20)

Amino Acid Sequence Animals Avian Proteins Blotting, Western Cell Adhesion Cell Adhesion Molecules Chick Embryo DNA Primers Epidermal Cells Epithelium Gastrula Gene Expression Regulation, Developmental Immunohistochemistry Intestines Molecular Sequence Data Muscle Proteins Muscles Reverse Transcriptase Polymerase Chain Reaction Skin Time Factors

Connections (2)

This publication is referenced by other Labnodes entities:

Links