Analysis of the effect of bulk at N2-alkylguanine DNA adducts on catalytic efficiency and fidelity of the processive DNA polymerases bacteriophage T7 exonuclease- and HIV-1 reverse transcriptase.

Choi JY, Guengerich FP
J Biol Chem. 2004 279 (18): 19217-29

PMID: 14985330 · DOI:10.1074/jbc.M313759200

MeSH Terms (14)

Alkylation Bacteriophage T7 Base Pair Mismatch Catalysis DNA Adducts Exodeoxyribonucleases Guanine HIV-1 HIV Reverse Transcriptase Kinetics Mutation Substrate Specificity Viral Proteins Virus Replication

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