Broad spectrum receptor tyrosine kinase inhibitor, SU6668, sensitizes radiation via targeting survival pathway of vascular endothelium.

Lu B, Geng L, Musiek A, Tan J, Cao C, Donnelly E, McMahon G, Choy H, Hallahan DE
Int J Radiat Oncol Biol Phys. 2004 58 (3): 844-50

PMID: 14967441 · DOI:10.1016/j.ijrobp.2003.10.049

MeSH Terms (16)

Animals Carcinoma, Lewis Lung Cell Line, Tumor Drug Evaluation, Preclinical Endothelium, Vascular Enzyme Activation Humans Indoles Mice Mice, Inbred C57BL Phosphorylation Protein-Serine-Threonine Kinases Proto-Oncogene Proteins Proto-Oncogene Proteins c-akt Pyrroles Receptor Protein-Tyrosine Kinases

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