Genetic Analysis Workshop II: results of segregation analyses using POINTER and linkage analyses using LIPED.

Cox NJ
Genet Epidemiol. 1984 1 (2): 167-70

PMID: 14964297 · DOI:10.1002/gepi.1370010208

Genetic Analysis Workshop II Problems 2 and 3 were analyzed using the segregation analysis program, POINTER and the linkage analysis program LIPED. Results of the segregation analyses were acceptable with respect to both parameter estimation and hypothesis testing. Results of the linkage analyses were also good. Although it was noted that the linkage and population association data were sometimes compatible with more than one hypothesis, the correct relationships among the trait and marker loci were generally among those found compatible with the data.

MeSH Terms (13)

Alleles Chromosome Segregation Gene Frequency Genetic Linkage Genetic Markers Humans Likelihood Functions Models, Genetic Multifactorial Inheritance Pedigree Penetrance Phenotype Software

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