Association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi.

Harbour JW, Brantley MA, Hollingsworth H, Gordon M
Br J Ophthalmol. 2004 88 (1): 36-8

PMID: 14693769 · PMCID: PMC1771959 · DOI:10.1136/bjo.88.1.36

AIM - To investigate the association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi.

METHODS - Cross sectional study of 65 patients with posterior uveal melanoma and 218 controls. Iris colour, iris freckles, iris naevi, and choroidal naevi were recorded for each eye of each patient.

RESULTS - Iris freckles were present in 40 (61.5%) patients with melanoma and 135 (61.9%) controls (p = 0.494). Iris naevi were present in four (6.2%) patients with melanoma and nine (4.1%) controls (p = 0.955). Choroidal naevi were present in 12 (18.5%) patients with melanoma and 38 (17.4%) controls (p = 0.815).

CONCLUSION - This study did not detect an association between posterior uveal melanoma and iris freckles, iris naevi, or choroidal naevi.

MeSH Terms (17)

Adult Aged Aged, 80 and over Choroid Neoplasms Cross-Sectional Studies Female Humans Iris Diseases Iris Neoplasms Male Melanoma Melanosis Middle Aged Neoplasms, Multiple Primary Nevus Prospective Studies Uveal Neoplasms

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