Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt.

Fukazawa R, Miller TA, Kuramochi Y, Frantz S, Kim YD, Marchionni MA, Kelly RA, Sawyer DB
J Mol Cell Cardiol. 2003 35 (12): 1473-9

PMID: 14654373 · DOI:10.1016/j.yjmcc.2003.09.012

MeSH Terms (21)

Adenoviridae Animals Animals, Newborn Anthracyclines Apoptosis Cells, Cultured Enzyme Activation ErbB Receptors Glycoproteins Heart Ventricles Myocardium Myocytes, Cardiac Neuregulin-1 Phosphatidylinositol 3-Kinases Protein Serine-Threonine Kinases Proto-Oncogene Proteins Proto-Oncogene Proteins c-akt Rats Rats, Sprague-Dawley Receptor, ErbB-2 Receptor, ErbB-4

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