Repeated administration of the anorectic factor prolactin-releasing peptide leads to tolerance to its effects on energy homeostasis.

Ellacott KL, Lawrence CB, Pritchard LE, Luckman SM
Am J Physiol Regul Integr Comp Physiol. 2003 285 (5): R1005-10

PMID: 14557233 · DOI:10.1152/ajpregu.00237.2003

MeSH Terms (21)

Adipose Tissue, Brown Animals Appetite Depressants Carrier Proteins Drug Tolerance Eating Energy Metabolism Gene Expression Homeostasis Hypothalamic Hormones Ion Channels Male Membrane Proteins Mitochondrial Proteins Neuropeptides Prolactin-Releasing Hormone Rats Rats, Sprague-Dawley Sympathetic Nervous System Uncoupling Protein 1 Weight Gain

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