A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice.

Heidet L, Borza DB, Jouin M, Sich M, Mattei MG, Sado Y, Hudson BG, Hastie N, Antignac C, Gubler MC
Am J Pathol. 2003 163 (4): 1633-44

PMID: 14507670 · PMCID: PMC1868284 · DOI:10.1016/s0002-9440(10)63520-1

MeSH Terms (17)

Animals Autoantibodies Autoantigens Basement Membrane Chimera Collagen Type IV Extracellular Matrix Proteins Humans Kidney Mice Mice, Knockout Mice, Transgenic Nephritis, Hereditary Phenotype Protein Isoforms Protein Subunits RNA, Messenger

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