Modification of cytochrome P450 1A2 enzymes by the mechanism-based inactivator 2-ethynylnaphthalene and the photoaffinity label 4-azidobiphenyl.

Yun CH, Hammons GJ, Jones G, Martin MV, Hopkins NE, Alworth WL, Guengerich FP
Biochemistry. 1992 31 (43): 10556-63

PMID: 1420171 · DOI:10.1021/bi00158a019

MeSH Terms (19)

Affinity Labels Amino Acid Sequence Animals Azides Biphenyl Compounds Chromatography, High Pressure Liquid Cytochrome P-450 CYP1A2 Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Enzyme System Humans Microsomes, Liver Molecular Sequence Data Naphthalenes Oxidoreductases Peptide Mapping Photochemistry Rabbits Rats Sequence Alignment

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