Cytotoxicity of quinolones toward eukaryotic cells. Identification of topoisomerase II as the primary cellular target for the quinolone CP-115,953 in yeast.

Elsea SH, Osheroff N, Nitiss JL
J Biol Chem. 1992 267 (19): 13150-3

PMID: 1320012

MeSH Terms (9)

Anti-Infective Agents Cell Survival DNA Damage DNA Topoisomerases, Type II Fluoroquinolones Mutation Quinolones Saccharomyces cerevisiae Topoisomerase II Inhibitors

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