Cellular vacuolation and mitochondrial cytochrome c release are independent outcomes of Helicobacter pylori vacuolating cytotoxin activity that are each dependent on membrane channel formation.

Willhite DC, Cover TL, Blanke SR
J Biol Chem. 2003 278 (48): 48204-9

PMID: 13129933 · DOI:10.1074/jbc.M304131200

MeSH Terms (16)

Anions Bacterial Proteins Cytochromes c Cytotoxins Dose-Response Relationship, Drug Green Fluorescent Proteins HeLa Cells Helicobacter pylori Humans Luminescent Proteins Macrolides Microscopy, Fluorescence Mitochondria Recombinant Fusion Proteins Time Factors Vacuoles

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