A role for the passage helix in the DNA cleavage reaction of eukaryotic topoisomerase II. A two-site model for enzyme-mediated DNA cleavage.

Corbett AH, Zechiedrich EL, Osheroff N
J Biol Chem. 1992 267 (2): 683-6

PMID: 1309770

MeSH Terms (11)

Animals Base Sequence DNA DNA Topoisomerases, Type II Drosophila melanogaster Electrophoresis, Polyacrylamide Gel Microscopy, Electron Molecular Sequence Data Nucleic Acid Conformation Oligonucleotides Substrate Specificity

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