Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis.

Chiang CW, Kanies C, Kim KW, Fang WB, Parkhurst C, Xie M, Henry T, Yang E
Mol Cell Biol. 2003 23 (18): 6350-62

PMID: 12944463 · PMCID: PMC193703 · DOI:10.1128/MCB.23.18.6350-6362.2003

MeSH Terms (22)

3T3 Cells 14-3-3 Proteins Animals Apoptosis bcl-Associated Death Protein bcl-X Protein Binding, Competitive Binding Sites Carrier Proteins Cells, Cultured Enzyme Inhibitors Humans Marine Toxins Mice Mutation Oxazoles Phosphoprotein Phosphatases Phosphorylation Phosphoserine Protein Phosphatase 2 Proto-Oncogene Proteins c-bcl-2 Tyrosine 3-Monooxygenase

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