Frataxin deficiency in pancreatic islets causes diabetes due to loss of beta cell mass.

Ristow M, Mulder H, Pomplun D, Schulz TJ, Müller-Schmehl K, Krause A, Fex M, Puccio H, Müller J, Isken F, Spranger J, Müller-Wieland D, Magnuson MA, Möhlig M, Koenig M, Pfeiffer AF
J Clin Invest. 2003 112 (4): 527-34

PMID: 12925693 · PMCID: PMC171391 · DOI:10.1172/JCI18107

MeSH Terms (21)

Alleles Animals Apoptosis Cell Division Diabetes Mellitus DNA, Complementary Exons Genotype Glucose Tolerance Test Insulin Insulin Secretion Iron-Binding Proteins Islets of Langerhans Magnetics Mice Mice, Inbred C57BL Mice, Knockout Microscopy, Fluorescence Reactive Oxygen Species Time Factors Tissue Distribution

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