TIGR is upregulated in the chronic glial scar in response to central nervous system injury and inhibits neurite outgrowth.

Jurynec MJ, Riley CP, Gupta DK, Nguyen TD, McKeon RJ, Buck CR
Mol Cell Neurosci. 2003 23 (1): 69-80

PMID: 12799138 · DOI:10.1016/s1044-7431(03)00019-8

MeSH Terms (20)

Animals Astrocytes Axotomy Brain Injuries Cells, Cultured Cerebral Cortex Chronic Disease Cicatrix Cytoskeletal Proteins Eye Proteins Gene Expression Glycoproteins Mice Nerve Regeneration Neurites Polymerase Chain Reaction Rats Sciatic Nerve Spinal Cord Injuries Up-Regulation

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