A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.

Zhou YP, Sreenan S, Pan CY, Currie KP, Bindokas VP, Horikawa Y, Lee JP, Ostrega D, Ahmed N, Baldwin AC, Cox NJ, Fox AP, Miller RJ, Bell GI, Polonsky KS
Metabolism. 2003 52 (5): 528-34

PMID: 12759879 · DOI:10.1053/meta.2003.50091

MeSH Terms (17)

Animals Calcium Calpain Cell Separation Cysteine Proteinase Inhibitors Dipeptides Energy Metabolism Glucose Insulin In Vitro Techniques Islets of Langerhans Leucine Mice Mice, Inbred C57BL Mitochondria NADP Oxidation-Reduction

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