Structural basis for bile acid binding and activation of the nuclear receptor FXR.

Mi LZ, Devarakonda S, Harp JM, Han Q, Pellicciari R, Willson TM, Khorasanizadeh S, Rastinejad F
Mol Cell. 2003 11 (4): 1093-100

PMID: 12718893 · DOI:10.1016/s1097-2765(03)00112-6

MeSH Terms (18)

Amino Acid Sequence Animals Bile Acids and Salts Binding Sites Cations Chemical Engineering DNA-Binding Proteins Hepatocytes Humans Hyperlipidemias Ligands Liver Molecular Conformation Molecular Sequence Data Molecular Structure Protein Structure, Tertiary Receptors, Cytoplasmic and Nuclear Transcription Factors

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