Minimal mutation of the cytoplasmic tail inhibits the ability of E-cadherin to activate Rac but not phosphatidylinositol 3-kinase: direct evidence of a role for cadherin-activated Rac signaling in adhesion and contact formation.

Goodwin M, Kovacs EM, Thoreson MA, Reynolds AB, Yap AS
J Biol Chem. 2003 278 (23): 20533-9

PMID: 12672818 · DOI:10.1074/jbc.M213171200

MeSH Terms (14)

Animals Cadherins Catenins Cell Adhesion Cell Adhesion Molecules CHO Cells Cricetinae Humans Mutagenesis Phosphatidylinositol 3-Kinases Phosphoproteins Protein Structure, Tertiary rac GTP-Binding Proteins Signal Transduction

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