Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.

Swisher SG, Roth JA, Komaki R, Gu J, Lee JJ, Hicks M, Ro JY, Hong WK, Merritt JA, Ahrar K, Atkinson NE, Correa AM, Dolormente M, Dreiling L, El-Naggar AK, Fossella F, Francisco R, Glisson B, Grammer S, Herbst R, Huaringa A, Kemp B, Khuri FR, Kurie JM, Liao Z, McDonnell TJ, Morice R, Morello F, Munden R, Papadimitrakopoulou V, Pisters KM, Putnam JB, Sarabia AJ, Shelton T, Stevens C, Shin DM, Smythe WR, Vaporciyan AA, Walsh GL, Yin M
Clin Cancer Res. 2003 9 (1): 93-101

PMID: 12538456

MeSH Terms (20)

Adenoviridae Aged Aged, 80 and over Apoptosis Carcinoma, Non-Small-Cell Lung Combined Modality Therapy Female Genes, p53 Genetic Therapy Genetic Vectors Gene Transfer Techniques Humans Lung Neoplasms Male Middle Aged Radiotherapy Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Time Factors Tumor Suppressor Protein p53

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