Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase.

Codreanu SG, Ladner JE, Xiao G, Stourman NV, Hachey DL, Gilliland GL, Armstrong RN
Biochemistry. 2002 41 (51): 15161-72

PMID: 12484753 · DOI:10.1021/bi026776p

MeSH Terms (21)

Amides Amino Acid Substitution Animals Catalysis Circular Dichroism Crystallization Crystallography, X-Ray Deuterium Oxide Dinitrochlorobenzene Glutathione Transferase Kinetics Mutagenesis, Site-Directed Phenylalanine Protein Conformation Protons Rats Spectrometry, Fluorescence Structure-Activity Relationship Substrate Specificity Thermodynamics Tyrosine

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