Nucleoside reverse transcriptase inhibitors impair endothelium-dependent relaxation by increasing superoxide.

Sutliff RL, Dikalov S, Weiss D, Parker J, Raidel S, Racine AK, Russ R, Haase CP, Taylor WR, Lewis W
Am J Physiol Heart Circ Physiol. 2002 283 (6): H2363-70

PMID: 12388299 · DOI:10.1152/ajpheart.00151.2002

MeSH Terms (21)

1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt Animals Aorta Cells, Cultured Dose-Response Relationship, Drug Electron Spin Resonance Spectroscopy Endothelium, Vascular Free Radical Scavengers In Vitro Techniques Male Mice Mice, Inbred Strains Nucleosides Reverse Transcriptase Inhibitors Stavudine Superoxides Vasoconstriction Vasoconstrictor Agents Vasodilation Vasodilator Agents Zidovudine

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