2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA.

Prakash TP, Manoharan M, Kawasaki AM, Fraser AS, Lesnik EA, Sioufi N, Leeds JM, Teplova M, Egli M
Biochemistry. 2002 41 (39): 11642-8

PMID: 12269806 · DOI:10.1021/bi020264t

MeSH Terms (10)

Binding Sites Crystallography, X-Ray Nucleic Acid Heteroduplexes Nucleosides Oligodeoxyribonucleotides Oligodeoxyribonucleotides, Antisense Organophosphorus Compounds Protein Binding RNA Uridine

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