The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.

Zhang P, McGrath BC, Reinert J, Olsen DS, Lei L, Gill S, Wek SA, Vattem KM, Wek RC, Kimball SR, Jefferson LS, Cavener DR
Mol Cell Biol. 2002 22 (19): 6681-8

PMID: 12215525 · PMCID: PMC134046 · DOI:10.1128/MCB.22.19.6681-6688.2002

MeSH Terms (26)

Adaptation, Physiological Animals Animals, Newborn Cells, Cultured Eukaryotic Initiation Factor-2 Eukaryotic Initiation Factor-2B Female Fetal Viability Food, Formulated Gene Expression Regulation Gene Targeting Glycine Heterozygote Homozygote Leucine Liver Mice Mice, Knockout Phosphorylation Pregnancy Prenatal Exposure Delayed Effects Protein-Serine-Threonine Kinases Protein Kinases Protein Subunits Stem Cells Tryptophan

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