A single mutation in the carboxy terminus of reovirus outer-capsid protein sigma 3 confers enhanced kinetics of sigma 3 proteolysis, resistance to inhibitors of viral disassembly, and alterations in sigma 3 structure.

Wilson GJ, Nason EL, Hardy CS, Ebert DH, Wetzel JD, Venkataram Prasad BV, Dermody TS
J Virol. 2002 76 (19): 9832-43

PMID: 12208961 · PMCID: PMC136532 · DOI:10.1128/jvi.76.19.9832-9843.2002

MeSH Terms (12)

Capsid Capsid Proteins Endocytosis Endopeptidases Kinetics Point Mutation Protein Conformation Recombinant Proteins RNA-Binding Proteins Structure-Activity Relationship Virion Virus Assembly

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