Publication

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia.

Linggi B, Müller-Tidow C, van de Locht L, Hu M, Nip J, Serve H, Berdel WE, van der Reijden B, Quelle DE, Rowley JD, Cleveland J, Jansen JH, Pandolfi PP, Hiebert SW
Nat Med. 2002 8 (7): 743-50

PMID: 12091906 · DOI:10.1038/nm726

MeSH Terms (21)

Antigens, CD CD4 Antigens Chromosomes, Human, Pair 8 Chromosomes, Human, Pair 21 Core Binding Factor Alpha 2 Subunit Gene Expression Regulation, Neoplastic Genes, Reporter Genes, Tumor Suppressor Hematopoietic Stem Cells Humans K562 Cells Leukemia, Myeloid, Acute Oncogene Proteins, Fusion Plasmids Repressor Proteins RUNX1 Translocation Partner 1 Protein Transcription, Genetic Transcription Factors Translocation, Genetic Tumor Cells, Cultured Tumor Suppressor Protein p14ARF

Connections (2)

This publication is referenced by other Labnodes entities:

Links