FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506.

Xu X, Su B, Barndt RJ, Chen H, Xin H, Yan G, Chen L, Cheng D, Heitman J, Zhuang Y, Fleischer S, Shou W
Transplantation. 2002 73 (11): 1835-8

PMID: 12085010 · DOI:10.1097/00007890-200206150-00023

MeSH Terms (12)

Animals CD3 Complex CD28 Antigens Cell Division Cyclosporine Dose-Response Relationship, Drug Immunosuppressive Agents Mice Mice, Knockout T-Lymphocytes Tacrolimus Tacrolimus Binding Protein 1A

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