1,N(2)-ethenoguanine, a mutagenic DNA adduct, is a primary substrate of Escherichia coli mismatch-specific uracil-DNA glycosylase and human alkylpurine-DNA-N-glycosylase.

Saparbaev M, Langou√ęt S, Privezentzev CV, Guengerich FP, Cai H, Elder RH, Laval J
J Biol Chem. 2002 277 (30): 26987-93

PMID: 12016206 · DOI:10.1074/jbc.M111100200

MeSH Terms (16)

Animals Cell-Free System DNA Adducts DNA Glycosylases DNA Repair Escherichia coli Guanine Humans Kinetics Mice Models, Chemical N-Glycosyl Hydrolases Oligonucleotides Protein Binding Substrate Specificity Uracil-DNA Glycosidase

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