The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas.

Zhang P, McGrath B, Li S, Frank A, Zambito F, Reinert J, Gannon M, Ma K, McNaughton K, Cavener DR
Mol Cell Biol. 2002 22 (11): 3864-74

PMID: 11997520 · PMCID: PMC133833 · DOI:10.1128/MCB.22.11.3864-3874.2002

MeSH Terms (18)

Animals Apoptosis Bone Development Bone Diseases, Developmental Cell Survival Collagen Type I Diabetes Mellitus eIF-2 Kinase Endoplasmic Reticulum, Rough Eukaryotic Initiation Factor-2 Gene Expression Glucose Growth Disorders Humans Mice Mice, Knockout Pancreas Phosphorylation

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