Accurate, noninvasive detection of Helicobacter pylori DNA from stool samples: potential usefulness for monitoring treatment.

Shuber AP, AscaƱo JJ, Boynton KA, Mitchell A, Frierson HF, El-Rifai W, Powell SM
J Clin Microbiol. 2002 40 (1): 262-4

PMID: 11773127 · PMCID: PMC120120 · DOI:10.1128/jcm.40.1.262-264.2002

A novel DNA assay demonstrating sensitive and accurate detection of Helicobacter pylori from stool samples is reported. Moreover, in three individuals tested for therapeutic response, the assay showed the disappearance of H. pylori DNA during treatment. Thus, this noninvasive molecular biology-based assay has the potential to be a powerful diagnostic tool given its ability to specifically identify H. pylori DNA.

MeSH Terms (7)

DNA, Bacterial Feces Helicobacter Infections Helicobacter pylori Humans Polymerase Chain Reaction Sensitivity and Specificity

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