Heterologous expression of cytochrome P450 2D6 mutants, electron transfer, and catalysis of bufuralol hydroxylation: the role of aspartate 301 in structural integrity.

Hanna IH, Kim MS, Guengerich FP
Arch Biochem Biophys. 2001 393 (2): 255-61

PMID: 11556812 · DOI:10.1006/abbi.2001.2510

MeSH Terms (15)

Adrenergic beta-Antagonists Aspartic Acid Catalysis Cytochrome P-450 CYP2D6 DNA, Complementary Electron Transport Escherichia coli Ethanolamines Ferric Compounds Gene Deletion Gene Expression Hydroxylation Mutation Oxidation-Reduction Protein Conformation

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