Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging.

Lorenz CH, Walker ES, Morgan VL, Klein SS, Graham TP
J Cardiovasc Magn Reson. 1999 1 (1): 7-21

PMID: 11550343 · DOI:10.3109/10976649909080829

Our objective was to establish normal ranges of left and right ventricular mass and function with cine magnetic resonance imaging (MRI) and to determine gender differences. Seventy-five healthy subjects (age range 8-55, mean 28 yr) were studied with cine MRI. Ten dogs were imaged for autopsy validation with a mean difference between actual and MRI-determined mass of 0.2 A +/- 8.4 g. Intraobserver and interobserver variability and interstudy variability were 5-6%. All parameters were significantly different between males and females except ejection fraction and the left ventricular mass to end-diastolic volume ratio. Agreement with published autopsy series, including gender differences, was excellent. This study presents normative MRI data that can be used for comparing individual patients and for further study of right and left ventricular interaction.

MeSH Terms (19)

Adolescent Adult Animals Cardiac Volume Child Dogs Female Humans Image Processing, Computer-Assisted Linear Models Magnetic Resonance Imaging, Cine Male Middle Aged Observer Variation Reference Values Sex Characteristics Systole Ventricular Function, Left Ventricular Function, Right

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